Publications
Fisher ML, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson JE, Goldberg GL, Mills AA. BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Cancer Res. 2021 Dec 15;81(24):6246-6258. doi: 10.1158/0008-5472.CAN-21-0707. Epub 2021 Oct 25. PubMed PMID: 34697072; PubMed Central PMCID: PMC8692924.
Fisher ML, Balinth S, Mills AA. ΔNp63α in cancer: importance and therapeutic opportunities. Trends Cell Biol. 2023 Apr;33(4):280-292. doi: 10.1016/j.tcb.2022.08.003. Epub 2022 Sep 14. Review. PubMed PMID: 36115734; PubMed Central PMCID: PMC10011024.
Fisher ML, Balinth S, Mills AA. p63-related signaling at a glance. J Cell Sci. 2020 Sep 11;133(17). doi: 10.1242/jcs.228015. Review. PubMed PMID: 32917730; PubMed Central PMCID: PMC7502597.
Hershlag A, Peyser A, Bristow SL, Puig O, Pollock A, Niknazar M, Mills AA. The potential impact of tumor suppressor genes on human gametogenesis: a case-control study. J Assist Reprod Genet. 2020 Feb;37(2):341-346. doi: 10.1007/s10815-019-01634-3. Epub 2019 Dec 2. PubMed PMID: 31792669; PubMed Central PMCID: PMC7056797.
Lu HC, Pollack H, Lefante JJ, Mills AA, Tian D. Altered sleep architecture, rapid eye movement sleep, and neural oscillation in a mouse model of human chromosome 16p11.2 microdeletion. Sleep. 2019 Mar 1;42(3). doi: 10.1093/sleep/zsy253. PubMed PMID: 30541142; PubMed Central PMCID: PMC7850008.
Hwang DW, Jaganathan A, Shrestha P, Jin Y, El-Amine N, Wang SH, Hammell M, Mills AA. Chromatin-mediated translational control is essential for neural cell fate specification. Life Sci Alliance. 2018 Aug;1(4):e201700016. doi: 10.26508/lsa.201700016. eCollection 2018 Aug. PubMed PMID: 30456361; PubMed Central PMCID: PMC6238594.
Lu HC, Mills AA, Tian D. Altered synaptic transmission and maturation of hippocampal CA1 neurons in a mouse model of human chr16p11.2 microdeletion. J Neurophysiol. 2018 Mar 1;119(3):1005-1018. doi: 10.1152/jn.00306.2017. Epub 2017 Dec 6. PubMed PMID: 29212915; PubMed Central PMCID: PMC7864230.
Mills AA. The Chromodomain Helicase DNA-Binding Chromatin Remodelers: Family Traits that Protect from and Promote Cancer. Cold Spring Harb Perspect Med. 2017 Apr 3;7(4). doi: 10.1101/cshperspect.a026450. Review. PubMed PMID: 28096241; PubMed Central PMCID: PMC5378010.
Taniguchi Y, Kawata M, Ho Chang S, Mori D, Okada K, Kobayashi H, Sugita S, Hosaka Y, Inui H, Taketomi S, Yano F, Ikeda T, Akiyama H, Mills AA, Chung UI, Tanaka S, Kawaguchi H, Saito T. Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63. Arthritis Rheumatol. 2017 Mar;69(3):598-609. doi: 10.1002/art.39976. PubMed PMID: 27792866.
Liu Y, Chen C, Xu Z, Scuoppo C, Rillahan CD, Gao J, Spitzer B, Bosbach B, Kastenhuber ER, Baslan T, Ackermann S, Cheng L, Wang Q, Niu T, Schultz N, Levine RL, Mills AA, Lowe SW. Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Nature. 2016 Mar 24;531(7595):471-475. doi: 10.1038/nature17157. Epub 2016 Mar 16. PubMed PMID: 26982726; PubMed Central PMCID: PMC4836395.
Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, Luo Clayton A, Biemans B. Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. PLoS One. 2015;10(8):e0134572. doi: 10.1371/journal.pone.0134572. eCollection 2015. PubMed PMID: 26273832; PubMed Central PMCID: PMC4537259.
Tian D, Stoppel LJ, Heynen AJ, Lindemann L, Jaeschke G, Mills AA, Bear MF. Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion. Nat Neurosci. 2015 Feb;18(2):182-4. doi: 10.1038/nn.3911. Epub 2015 Jan 12. PubMed PMID: 25581360; PubMed Central PMCID: PMC4323380.
Li W, Mills AA. Packing for the journey: CHD5 remodels the genome. Cell Cycle. 2014;13(12):1833-4. doi: 10.4161/cc.29378. Epub 2014 May 27. PubMed PMID: 24865185; PubMed Central PMCID: PMC4111744.
Li W, Wu J, Kim SY, Zhao M, Hearn SA, Zhang MQ, Meistrich ML, Mills AA. Chd5 orchestrates chromatin remodelling during sperm development. Nat Commun. 2014 May 13;5:3812. doi: 10.1038/ncomms4812. PubMed PMID: 24818823; PubMed Central PMCID: PMC4151132.
Li W, Mills AA. Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromes. Epigenomics. 2014;6(4):381-95. doi: 10.2217/epi.14.31. Review. PubMed PMID: 25333848; PubMed Central PMCID: PMC4233650.
Vestin A, Mills AA. The tumor suppressor Chd5 is induced during neuronal differentiation in the developing mouse brain. Gene Expr Patterns. 2013 Dec;13(8):482-9. doi: 10.1016/j.gep.2013.09.003. Epub 2013 Oct 9. PubMed PMID: 24120991; PubMed Central PMCID: PMC3855250.
Laronda MM, Unno K, Ishi K, Serna VA, Butler LM, Mills AA, Orvis GD, Behringer RR, Deng C, Sinha S, Kurita T. Diethylstilbestrol induces vaginal adenosis by disrupting SMAD/RUNX1-mediated cell fate decision in the Müllerian duct epithelium. Dev Biol. 2013 Sep 1;381(1):5-16. doi: 10.1016/j.ydbio.2013.06.024. Epub 2013 Jul 4. PubMed PMID: 23830984; PubMed Central PMCID: PMC3947918.
Kim SY, Cordeiro MH, Serna VA, Ebbert K, Butler LM, Sinha S, Mills AA, Woodruff TK, Kurita T. Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death Differ. 2013 Aug;20(8):987-97. doi: 10.1038/cdd.2013.31. Epub 2013 Apr 19. PubMed PMID: 23598363; PubMed Central PMCID: PMC3705595.
Ramsey MR, Wilson C, Ory B, Rothenberg SM, Faquin W, Mills AA, Ellisen LW. FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma. J Clin Invest. 2013 Aug;123(8):3525-38. doi: 10.1172/JCI68899. Epub 2013 Jul 8. PubMed PMID: 23867503; PubMed Central PMCID: PMC3726171.
Vernersson Lindahl E, Garcia EL, Mills AA. An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71. doi: 10.1002/ajmg.a.36074. Epub 2013 Jun 14. PubMed PMID: 23775923; PubMed Central PMCID: PMC4066377.
Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD. FANCD2 activates transcription of TAp63 and suppresses tumorigenesis. Mol Cell. 2013 Jun 27;50(6):908-18. doi: 10.1016/j.molcel.2013.05.017. PubMed PMID: 23806336; PubMed Central PMCID: PMC3897475.
Paul S, Kuo A, Schalch T, Vogel H, Joshua-Tor L, McCombie WR, Gozani O, Hammell M, Mills AA. Chd5 requires PHD-mediated histone 3 binding for tumor suppression. Cell Rep. 2013 Jan 31;3(1):92-102. doi: 10.1016/j.celrep.2012.12.009. Epub 2013 Jan 10. PubMed PMID: 23318260; PubMed Central PMCID: PMC3575599.
Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, Strasser A. DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa. Mol Cell. 2012 Nov 9;48(3):343-52. doi: 10.1016/j.molcel.2012.08.017. Epub 2012 Sep 20. PubMed PMID: 23000175; PubMed Central PMCID: PMC3496022.
Horev G, Ellegood J, Lerch JP, Son YE, Muthuswamy L, Vogel H, Krieger AM, Buja A, Henkelman RM, Wigler M, Mills AA. Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17076-81. doi: 10.1073/pnas.1114042108. Epub 2011 Oct 3. PubMed PMID: 21969575; PubMed Central PMCID: PMC3193230.
Keyes WM, Pecoraro M, Aranda V, Vernersson-Lindahl E, Li W, Vogel H, Guo X, Garcia EL, Michurina TV, Enikolopov G, Muthuswamy SK, Mills AA. ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell. 2011 Feb 4;8(2):164-76. doi: 10.1016/j.stem.2010.12.009. PubMed PMID: 21295273; PubMed Central PMCID: PMC4373450.
Mills AA. Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat Rev Cancer. 2010 Oct;10(10):669-82. doi: 10.1038/nrc2931. Review. PubMed PMID: 20865010; PubMed Central PMCID: PMC4068012.
Moretti F, Marinari B, Lo Iacono N, Botti E, Giunta A, Spallone G, Garaffo G, Vernersson-Lindahl E, Merlo G, Mills AA, Ballarò C, Alemà S, Chimenti S, Guerrini L, Costanzo A. A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest. 2010 May;120(5):1570-7. doi: 10.1172/JCI40267. Epub 2010 Apr 26. PubMed PMID: 20424325; PubMed Central PMCID: PMC2860936.
Vernersson-Lindahl E, Mills AA. {Delta}Np73{beta} puts the brakes on DNA repair. Genes Dev. 2010 Mar 15;24(6):517-20. doi: 10.1101/gad.1914210. PubMed PMID: 20231313; PubMed Central PMCID: PMC2841329.
Guo X, Keyes WM, Papazoglu C, Zuber J, Li W, Lowe SW, Vogel H, Mills AA. TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol. 2009 Dec;11(12):1451-7. doi: 10.1038/ncb1988. Epub 2009 Nov 8. PubMed PMID: 19898465; PubMed Central PMCID: PMC2920298.
Boles MK, Wilkinson BM, Maxwell A, Lai L, Mills AA, Nishijima I, Salinger AP, Moskowitz I, Hirschi KK, Liu B, Bradley A, Justice MJ. A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet. 2009 Mar 6;10:12. doi: 10.1186/1471-2156-10-12. PubMed PMID: 19267930; PubMed Central PMCID: PMC2670824.
Bagchi A, Mills AA. The quest for the 1p36 tumor suppressor. Cancer Res. 2008 Apr 15;68(8):2551-6. doi: 10.1158/0008-5472.CAN-07-2095. Review. PubMed PMID: 18413720; PubMed Central PMCID: PMC2980353.
Lo Iacono N, Mantero S, Chiarelli A, Garcia E, Mills AA, Morasso MI, Costanzo A, Levi G, Guerrini L, Merlo GR. Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development. 2008 Apr;135(7):1377-88. doi: 10.1242/dev.011759. PubMed PMID: 18326838.
Suzuki K, Haraguchi R, Ogata T, Barbieri O, Alegria O, Vieux-Rochas M, Nakagata N, Ito M, Mills AA, Kurita T, Levi G, Yamada G. Abnormal urethra formation in mouse models of split-hand/split-foot malformation type 1 and type 4. Eur J Hum Genet. 2008 Jan;16(1):36-44. doi: 10.1038/sj.ejhg.5201925. Epub 2007 Sep 19. PubMed PMID: 17878916.
Mignone JL, Roig-Lopez JL, Fedtsova N, Schones DE, Manganas LN, Maletic-Savatic M, Keyes WM, Mills AA, Gleiberman A, Zhang MQ, Enikolopov G. Neural potential of a stem cell population in the hair follicle. Cell Cycle. 2007 Sep 1;6(17):2161-70. doi: 10.4161/cc.6.17.4593. Epub 2007 Jun 13. PubMed PMID: 17873521; PubMed Central PMCID: PMC3789384.
Bagchi A, Papazoglu C, Wu Y, Capurso D, Brodt M, Francis D, Bredel M, Vogel H, Mills AA. CHD5 is a tumor suppressor at human 1p36. Cell. 2007 Feb 9;128(3):459-75. doi: 10.1016/j.cell.2006.11.052. PubMed PMID: 17289567.
Guo X, Mills AA. p63, cellular senescence and tumor development. Cell Cycle. 2007 Feb 1;6(3):305-11. doi: 10.4161/cc.6.3.3794. Epub 2007 Feb 3. Review. PubMed PMID: 17224650.
Papazoglu C, Mills AA. p53: at the crossroad between cancer and ageing. J Pathol. 2007 Jan;211(2):124-33. doi: 10.1002/path.2086. Review. PubMed PMID: 17200941.
Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH, Kushida M, Qiu W, Mills AA, Kim PC. DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development. 2006 Dec;133(23):4783-92. doi: 10.1242/dev.02621. Epub 2006 Nov 1. PubMed PMID: 17079275.
Carroll DK, Carroll JS, Leong CO, Cheng F, Brown M, Mills AA, Brugge JS, Ellisen LW. p63 regulates an adhesion programme and cell survival in epithelial cells. Nat Cell Biol. 2006 Jun;8(6):551-61. doi: 10.1038/ncb1420. Epub 2006 May 21. PubMed PMID: 16715076.
Keyes WM, Vogel H, Koster MI, Guo X, Qi Y, Petherbridge KM, Roop DR, Bradley A, Mills AA. p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8435-40. doi: 10.1073/pnas.0602477103. Epub 2006 May 19. PubMed PMID: 16714381; PubMed Central PMCID: PMC1482510.
Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006 Apr;133(8):1553-63. doi: 10.1242/dev.02325. Epub 2006 Mar 8. PubMed PMID: 16524929.
Mills AA. p63: oncogene or tumor suppressor?. Curr Opin Genet Dev. 2006 Feb;16(1):38-44. doi: 10.1016/j.gde.2005.12.001. Epub 2005 Dec 15. Review. PubMed PMID: 16359856.
Keyes WM, Mills AA. p63: a new link between senescence and aging. Cell Cycle. 2006 Feb;5(3):260-5. doi: 10.4161/cc.5.3.2415. Epub 2006 Feb 1. Review. PubMed PMID: 16434880.
Jacobs WB, Govoni G, Ho D, Atwal JK, Barnabe-Heider F, Keyes WM, Mills AA, Miller FD, Kaplan DR. p63 is an essential proapoptotic protein during neural development. Neuron. 2005 Dec 8;48(5):743-56. doi: 10.1016/j.neuron.2005.10.027. PubMed PMID: 16337913.
Mills AA. p53: link to the past, bridge to the future. Genes Dev. 2005 Sep 15;19(18):2091-9. doi: 10.1101/gad.1362905. Review. PubMed PMID: 16166374.
Kurita T, Cunha GR, Robboy SJ, Mills AA, Medina RT. Differential expression of p63 isoforms in female reproductive organs. Mech Dev. 2005 Sep;122(9):1043-55. doi: 10.1016/j.mod.2005.04.008. PubMed PMID: 15922574.
Keyes WM, Wu Y, Vogel H, Guo X, Lowe SW, Mills AA. p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev. 2005 Sep 1;19(17):1986-99. doi: 10.1101/gad.342305. Epub 2005 Aug 17. PubMed PMID: 16107615; PubMed Central PMCID: PMC1199570.
Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD. Perp is a p63-regulated gene essential for epithelial integrity. Cell. 2005 Mar 25;120(6):843-56. doi: 10.1016/j.cell.2005.01.008. PubMed PMID: 15797384.
Kurita T, Medina RT, Mills AA, Cunha GR. Role of p63 and basal cells in the prostate. Development. 2004 Oct;131(20):4955-64. doi: 10.1242/dev.01384. Epub 2004 Sep 15. PubMed PMID: 15371309.
Kurita T, Mills AA, Cunha GR. Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis. Development. 2004 Apr;131(7):1639-49. doi: 10.1242/dev.01038. Epub 2004 Mar 3. PubMed PMID: 14998922.
Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev. 2004 Jan 15;18(2):126-31. doi: 10.1101/gad.1165104. Epub 2004 Jan 16. PubMed PMID: 14729569; PubMed Central PMCID: PMC324418.
Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ. Dicer is essential for mouse development. Nat Genet. 2003 Nov;35(3):215-7. doi: 10.1038/ng1253. Epub 2003 Oct 5. PubMed PMID: 14528307.
Nishijima I, Mills A, Qi Y, Mills M, Bradley A. Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8. doi: 10.1002/gene.10207. PubMed PMID: 12872245.
Keyes WM, Mills AA. Inducible systems see the light. Trends Biotechnol. 2003 Feb;21(2):53-5. doi: 10.1016/s0167-7799(02)00022-7. PubMed PMID: 12573850.
Garcia EL, Mills AA. Getting around lethality with inducible Cre-mediated excision. Semin Cell Dev Biol. 2002 Apr;13(2):151-8. doi: 10.1016/s1084-9521(02)00019-8. Review. PubMed PMID: 12127267.
Mills AA, Qi Y, Bradley A. Conditional inactivation of p63 by Cre-mediated excision. Genesis. 2002 Feb;32(2):138-41. doi: 10.1002/gene.10067. PubMed PMID: 11857801.
Su H, Mills AA, Wang X, Bradley A. A targeted X-linked CMV-Cre line. Genesis. 2002 Feb;32(2):187-8. doi: 10.1002/gene.10043. PubMed PMID: 11857817.
Mills AA. Changing colors in mice: an inducible system that delivers. Genes Dev. 2001 Jun 15;15(12):1461-7. doi: 10.1101/gad.909301. Review. PubMed PMID: 11410526.
Mills AA, Bradley A. From mouse to man: generating megabase chromosome rearrangements. Trends Genet. 2001 Jun;17(6):331-9. doi: 10.1016/s0168-9525(01)02321-6. Review. PubMed PMID: 11377795.
Zheng B, Mills AA, Bradley A. Introducing defined chromosomal rearrangements into the mouse genome. Methods. 2001 May;24(1):81-94. doi: 10.1006/meth.2001.1160. PubMed PMID: 11327806.
Zheng B, Mills AA, Bradley A. A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res. 1999 Jun 1;27(11):2354-60. doi: 10.1093/nar/27.11.2354. PubMed PMID: 10325425; PubMed Central PMCID: PMC148802.
Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 1999 Apr 22;398(6729):708-13. doi: 10.1038/19531. PubMed PMID: 10227293.
Mills AA, Mills MJ, Gardiner DM, Bryant SV, Stanbridge EJ. Analysis of the pattern of QM expression during mouse development. Differentiation. 1999 Mar;64(3):161-71. doi: 10.1046/j.1432-0436.1999.6430161.x. PubMed PMID: 10234813.
Nguyen YH, Mills AA, Stanbridge EJ. Assembly of the QM protein onto the 60S ribosomal subunit occurs in the cytoplasm. J Cell Biochem. 1998 Feb 1;68(2):281-5. PubMed PMID: 9443083.
Farmer AA, Loftus TM, Mills AA, Sato KY, Neill JD, Tron T, Yang M, Trumpower BL, Stanbridge EJ. Extreme evolutionary conservation of QM, a novel c-Jun associated transcription factor. Hum Mol Genet. 1994 May;3(5):723-8. doi: 10.1093/hmg/3.5.723. PubMed PMID: 8081358.
Stanbridge E, Farmer A, Mills A, Loftus T, Kongkasuriyachai D, Dowdy S, Weissman B. Molecular characterization of QM, a novel gene with properties consistent with tumor suppressor function. Cold Spring Harb Symp Quant Biol. 1994;59:573-6. doi: 10.1101/sqb.1994.059.01.064. PubMed PMID: 7587114.
Harth G, Mills AA, Lin T, Araujo FG. Trypanosoma cruzi glycoprotein of M(r) 56,000 characterization and assessment of its potential to protect against fatal parasite infections. Mol Microbiol. 1994 Jan;11(2):261-71. doi: 10.1111/j.1365-2958.1994.tb00306.x. PubMed PMID: 8170388.
Harth G, Andrews N, Mills AA, Engel JC, Smith R, McKerrow JH. Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi. Mol Biochem Parasitol. 1993 Mar;58(1):17-24. doi: 10.1016/0166-6851(93)90086-d. PubMed PMID: 8459830.
Eakin AE, Mills AA, Harth G, McKerrow JH, Craik CS. The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi. J Biol Chem. 1992 Apr 15;267(11):7411-20. PubMed PMID: 1559982.
Harth G, Mills AA, Souto-Padrón T, de Souza W. Trypanosoma cruzi glycoprotein 72: immunological analysis and cellular localization. Mol Cell Biochem. 1992 Jan 15;109(1):25-36. doi: 10.1007/bf00230870. PubMed PMID: 1614419.
Sun X, Klingbeil O, Lu B, Wu C, Ballon C, Ouyang M, Wu XS, Jin Y, Hwangbo Y, Huang YH, Somerville TDD, Chang K, Park J, Chung T, Lyons SK, Shi J, Vogel H, Schulder M, Vakoc CR, Mills AA. BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network. Nature. 2023 Jan;613(7942):195-202. doi: 10.1038/s41586-022-05551-x. Epub 2022 Dec 21. PubMed PMID: 36544023; NIHMSID:NIHMS1875086.
Balinth S, Fisher ML, Hwangbo Y, Wu C, Ballon C, Sun X, Mills AA. EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma. Oncogene. 2022 Aug;41(35):4130-4144. doi: 10.1038/s41388-022-02417-4. Epub 2022 Jul 21. PubMed PMID: 35864175; PubMed Central PMCID: PMC10132824.
Shrestha P, Jaganathan A, Huilgol D, Ballon C, Hwangbo Y, Mills AA. Chd5 Regulates the Transcription Factor Six3 to Promote Neuronal Differentiation. Stem Cells. 2023 Mar 17;41(3):242-251. doi: 10.1093/stmcls/sxad002. PubMed PMID: 36636025; PubMed Central PMCID: PMC10020979.